RECRUITING

Personalized Theta-burst Stimulation for Long-lasting Changes in Approach/Avoidance Behavior

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will assess the long-lasting effects of personalized theta burst stimulation (TBS), a repetitive form of transcranial magnetic stimulation (TMS), over the left prefrontal cortex on the approach/avoidance behavior. TBS will be personalized based on the prefrontal theta rhythm captured with electroencephalography (EEG). The main questions it aims to answer are: 1. does a single session of personalized TBS synchronized with the individual theta rhythm over the left prefrontal cortex results in the outlasting changes in the individual behavior? 2. Does TBS results in the brain rhythms' changes as measured using resting-state EEG?

Official Title

The Efficiency of Personalized Theta-burst Stimulation for Inducing Long-lasting Changes in DLPFC

Quick Facts

Study Start:2025-07-31
Study Completion:2026-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07161505

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Participants must be legal adults between the ages of 18 to 65;
  2. 2. Able and willing to complete study procedures and tasks.
  1. 1. History or evidence of chronic neurological or mental disorder;
  2. 2. Chronic condition that requires pharmacological treatment over the course of study participation;
  3. 3. Pregnancy or breastfeeding;
  4. 4. History or evidence of alcohol or drug addiction;
  5. 5. Contraindications for transcranial magnetic stimulation (history of seizures, metallic or electric implant in the head/neck area);
  6. 6. Contraindications for magnetic resonance imaging at 3 Tesla (non-compatible implants, metallic foreign bodies, insulin pump, pacemaker).

Contacts and Locations

Study Contact

Ivan Alekseichuk, PhD
CONTACT
312-503-3196
neuromodlab@northwestern.edu

Principal Investigator

Ivan Alekseichuk, PhD
PRINCIPAL_INVESTIGATOR
Northwestern University

Study Locations (Sites)

Northwestern University Feinberg School of Medicine
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: Northwestern University

  • Ivan Alekseichuk, PhD, PRINCIPAL_INVESTIGATOR, Northwestern University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-31
Study Completion Date2026-08-31

Study Record Updates

Study Start Date2025-07-31
Study Completion Date2026-08-31

Terms related to this study

Additional Relevant MeSH Terms

  • Approach/Avoidance Behavior