RECRUITING

Pregnancy 24/7 Offspring Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

There is growing evidence that maternal health and behaviors in pregnancy, such as pre-pregnancy obesity, excessive gestational weight gain, poor diet, smoking, and adverse pregnancy outcomes, are linked to fetal programming for obesity and cardiovascular disease (CVD) risk in the offspring. Yet, there is a surprising lack of research on the role of prenatal sedentary behavior, physical activity, and sleep (conceptualized together as 24-hour behavior) on offspring obesity risk and CVD risk; this is an unfortunate research gap since there is strong physiological rationale that these behaviors in pregnancy could influence offspring health and are modifiable intervention targets in pregnancy. This multi-site observational cohort study will leverage state-of-the-art, 24-hour behavior assessment in each trimester of pregnancy, collected as part of the Pregnancy 24/7 cohort study and add additional assessments of offspring growth, adiposity, and CVD risk through 24 months to inform future primordial prevention interventions to decrease the risk of offspring obesity and CVD across the lifespan.

Official Title

Sedentary Behavior, Physical Activity, and 24-hour Behavior in Pregnancy and Offspring Health: the Pregnancy 24/7 Offspring Study

Quick Facts

Study Start:2023-07-01
Study Completion:2027-07-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07172880

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:0 Years to 47 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Enrolled in Pregnancy 24/7 Study.
  2. * Completed at least one 24-hr behavior assessment, with valid objective activity monitor data and questionnaires.
  3. * Pregnancy resulted in singleton live birth.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Kara M Whitaker, PhD, MPH
CONTACT
319-335-7907
kara-whitaker@uiowa.edu

Principal Investigator

Kara M Whitaker, PhD, MPH
PRINCIPAL_INVESTIGATOR
University of Iowa
Bethany Barone Gibbs, PhD
PRINCIPAL_INVESTIGATOR
West Virginia University
Sharon Ross, PhD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

University of Iowa
Iowa City, Iowa, 52242
United States
University of Pittsburgh
Pittsburgh, Pennsylvania, 15213
United States
West Virginia University
Morgantown, West Virginia, 26506
United States

Collaborators and Investigators

Sponsor: Kara Whitaker

  • Kara M Whitaker, PhD, MPH, PRINCIPAL_INVESTIGATOR, University of Iowa
  • Bethany Barone Gibbs, PhD, PRINCIPAL_INVESTIGATOR, West Virginia University
  • Sharon Ross, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-01
Study Completion Date2027-07-06

Study Record Updates

Study Start Date2023-07-01
Study Completion Date2027-07-06

Terms related to this study

Keywords Provided by Researchers

  • Physical Activity
  • Sleep
  • Sedentary Behavior
  • Cardiovascular Disease Risk
  • Obesity Risk
  • Growth and Development
  • 24- Hour Movement Behaviors
  • Children
  • Pregnancy

Additional Relevant MeSH Terms

  • Healthy