RECRUITING

Scrambler Therapy in Chronic Pancreatitis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators will enroll adults with chronic pancreatitis who have persistent abdominal pain not relieved by standard treatments. This study will test the feasibility and effectiveness of Scrambler Therapy, a non-invasive FDA-cleared device that delivers "non-pain" electrical signals through the skin to retrain the brain's pain perception. Participants will undergo 5-10 treatment sessions and be followed for 3 months with standardized pain scores and quality-of-life assessments. The goal is to generate pilot data to support larger studies of Scrambler Therapy as a novel option for pancreatic pain.

Official Title

A Pilot Study of Scrambler Therapy for Painful Chronic Pancreatitis

Quick Facts

Study Start:2024-11-01
Study Completion:2026-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07174609

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adults aged 18 years and older
  2. * Diagnosis of chronic pancreatitis with refractory abdominal pain
  3. * Able to provide written informed consent in English
  4. * Sufficient English language ability to complete study questionnaires
  5. * Reliable and regular access to a phone for follow-up
  1. * Unable or unwilling to provide written consent
  2. * History or presence of a significant medical or psychiatric condition that would interfere with study participation
  3. * Pregnant or lactating women
  4. * Coronary stents or implanted metallic/electrical devices (pacemaker, defibrillator, aneurysm clips)
  5. * History of epilepsy, traumatic brain injury, or myocardial infarction within the past 6 months
  6. * Skin conditions preventing electrode placement (e.g., open wounds)
  7. * Any condition that, in the investigator's opinion, places the participant at increased risk or prevents full compliance with study procedures

Contacts and Locations

Study Contact

Mahya Faghih
CONTACT
443-287-4680
mfaghih2@jh.edu

Principal Investigator

Mahya Faghih
PRINCIPAL_INVESTIGATOR
Johns Hopkins University

Study Locations (Sites)

Johns Hopkins Green Spring Station
Baltimore, Maryland, 21205
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Mahya Faghih, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-11-01
Study Completion Date2026-12-01

Study Record Updates

Study Start Date2024-11-01
Study Completion Date2026-12-01

Terms related to this study

Keywords Provided by Researchers

  • chronic pain
  • Abdominal pain
  • chronic pancreatitis
  • Scrambler Therapy
  • Electrocutaneous analgesia

Additional Relevant MeSH Terms

  • Chronic Pain
  • Pancreatitis
  • Chronic Pancreatitis