RECRUITING

Criterion-learning Naming Treatment For Addressing Comprehension Deficits in Aphasia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Aphasia is a disorder of spoken and written language, most commonly following a stroke. It is estimated that between 2.5 and 4 million Americans are living with aphasia today. A common problem in aphasia involves difficulty retrieving known words in the course of language production and comprehension. The overarching goal of this project is to develop and test early efficacy, efficiency, and the tolerability of a lexical treatment for aphasia in multiple-session regimens that are comprised of retrieval practice, distributed practice, and training dedicated to the elicitation of correct retrievals. The aim of this work is to add to and refine the evidence base for the implementation and optimization of these elements in the treatment of production and comprehension deficits in aphasia, and make important steps towards an ultimate goal of self-administered lexical treatment grounded in retrieval practice principles (RPP) to supplement traditional speech-language therapy that is appropriate for People with Aphasia (PWA) from a broad level of severity of lexical processing deficit in naming and/or comprehension. This project cumulatively builds on prior work to develop a theory of learning for lexical processing impairment in aphasia that aims to ultimately explain why and for whom familiar lexical treatments work, and how to maximize the benefits they confer.

Official Title

Word Retrieval in Aphasia

Quick Facts

Study Start:2024-06-24
Study Completion:2028-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07179458

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 89 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * English as a native or primary language
  2. * Adults with stroke who are at least 6 months post-onset
  3. * Exhibit semantic comprehension deficit, defined as a minimum of 80 errors on word-picture verification pre-test
  1. * History of comorbid neurological diagnoses, such as Multiple Sclerosis or Parkinson's Disease
  2. * History of a learning disability that significantly impacted language development, such as developmental language disorder
  3. * Insufficient stamina to participate in the protocol

Contacts and Locations

Study Contact

Kelly Horel, CCC SLP
CONTACT
215-663-6017
kelly.horel@jefferson.edu

Principal Investigator

Erica L Middleton, PhD
PRINCIPAL_INVESTIGATOR
Albert Einstein Healthcare Network

Study Locations (Sites)

Jefferson Moss Rehabilitation Research Institute
Elkins Park, Pennsylvania, 19027
United States

Collaborators and Investigators

Sponsor: Albert Einstein Healthcare Network

  • Erica L Middleton, PhD, PRINCIPAL_INVESTIGATOR, Albert Einstein Healthcare Network

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-06-24
Study Completion Date2028-08

Study Record Updates

Study Start Date2024-06-24
Study Completion Date2028-08

Terms related to this study

Keywords Provided by Researchers

  • anomia
  • retrieval practice
  • word-finding problem
  • communication disorder
  • naming impairment
  • word comprehension impairment

Additional Relevant MeSH Terms

  • Aphasia