RECRUITING

Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Many consider laser enucleation of the prostate the new 'gold standard' for the surgical treatment of benign prostatic hyperplasia (BPH) due to its excellent outcomes, high success rates, and long-term efficacy. Holmium laser enucleation of the prostate (HoLEP) was the earliest form of prostate enucleation and is recommended by the American Urological Association (AUA), along with thulium laser enucleation of the prostate (ThuLEP), as size-independent techniques for the management of BPH with fewer complications than transurethral resection of the prostate (TURP). Further development of laser technology has additionally led to enucleation using pulsed-modulated (e.g. "Virtual Basket™" mode or MOSES™ mode) holmium lasers as well as the thulium fiber laser.

Official Title

Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate

Quick Facts

Study Start:2025-06-02
Study Completion:2026-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07187180

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Understand and voluntarily sign an informed consent form.
  2. * Patients must be males with a prostate, at least 18 years of age
  3. * No prior prostate surgery
  1. * Unable/refuse to provide informed consent
  2. * Prior prostate surgery
  3. * Bladder stones that requiring lasering (small stone that can be removed whole is ok)
  4. * Unable to hold anticoagulants or antiplatelets per standard protocols for surgery and up to 1 week postop.

Contacts and Locations

Study Contact

Iva Markovic
CONTACT
216-636-9694
markovi@ccf.org
Smita De, MD, PHD
CONTACT
216-445-4818
des@ccf.org

Study Locations (Sites)

Cleveland Clinic Main
Cleveland, Ohio, 44195
United States

Collaborators and Investigators

Sponsor: Smita De

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-06-02
Study Completion Date2026-09

Study Record Updates

Study Start Date2025-06-02
Study Completion Date2026-09

Terms related to this study

Keywords Provided by Researchers

  • BPH
  • Enlarged prostate
  • Thulio laser
  • Prostate enucleation
  • male urinary retention

Additional Relevant MeSH Terms

  • BPH With Symptomatic Lower Urinary Tract Symptoms
  • BPH With Urinary Obstruction