RECRUITING

Low-Dose Ketamine Infusion During Burn Wound Care

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.

Official Title

A Randomized, Placebo-Controlled, Double-Blind Evaluation of Low-Dose Ketamine Infusion During Burn Wound Care Procedures to Improve Pain Intensity and Reduce Opioid Consumption

Quick Facts

Study Start:2024-07-08
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06506565

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Admitted to burn service with thermal injury
  1. * unable/unwilling to consent within 72 hours
  2. * unable to report NRS
  3. * known contraindication to ketamine
  4. * \< than 18 years of age
  5. * pregnant
  6. * incarcerated
  7. * TBSA over 50 %

Contacts and Locations

Study Contact

David M Hill, Pharm.D.
CONTACT
1-901-545-7100
dhill19@uthsc.edu

Study Locations (Sites)

Regional One Health
Memphis, Tennessee, 38103
United States

Collaborators and Investigators

Sponsor: University of Tennessee

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-08
Study Completion Date2025-12

Study Record Updates

Study Start Date2024-07-08
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • ketamine
  • burn
  • opioid
  • analgesia

Additional Relevant MeSH Terms

  • Burn
  • Pain
  • Dissociation
  • Opioid