RECRUITING

Walnuts as an Infant Solid Food for Health

Description

The objective is to investigate the effect of walnuts on gut microbiota, inflammatory markers, atopic dermatitis status, and indices of allergy outcomes in breastfed infants during early complementary feeding. The three primary aims include: Aim 1: Evaluate the effect of walnut consumption on gut microbiota structure and function, inflammation, atopic dermatitis, and allergy outcomes. Aim 2: Evaluate the impact of walnut consumption on infant growth trajectories and risk of overweight. Aim 3 (exploratory): Identify walnut-specific food signatures that are associated with gut microbiota and immunity biomarkers using a novel nutri-metabolomics technique.

Study Overview

Study Details

Study overview

The objective is to investigate the effect of walnuts on gut microbiota, inflammatory markers, atopic dermatitis status, and indices of allergy outcomes in breastfed infants during early complementary feeding. The three primary aims include: Aim 1: Evaluate the effect of walnut consumption on gut microbiota structure and function, inflammation, atopic dermatitis, and allergy outcomes. Aim 2: Evaluate the impact of walnut consumption on infant growth trajectories and risk of overweight. Aim 3 (exploratory): Identify walnut-specific food signatures that are associated with gut microbiota and immunity biomarkers using a novel nutri-metabolomics technique.

Walnut as a First Food During Complementary Feeding on Gut Microbiota and Immunity Development in Breastfed Infants

Walnuts as an Infant Solid Food for Health

Condition
Gut -Microbiota
Intervention / Treatment

-

Contacts and Locations

Fort Collins

Food Science and Human Nutrition Clinical Research Laboratory, Fort Collins, Colorado, United States, 80523

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Full term: gestational age ≥ 37 weeks
  • * Generally healthy without conditions that would affect normal growth
  • * No significant consumption of complementary food (e.g., no more than 1 oz of solid foods per week)
  • * Exclusively breastfed (\< 2 weeks of cumulative formula exposure)
  • * Adults unable to consent
  • * Pregnant women
  • * Prisoners

Ages Eligible for Study

5 Months to 5 Months

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Colorado State University,

Minghua Tang, Phd, PRINCIPAL_INVESTIGATOR, Colorado State University

Study Record Dates

2027-12-31