RECRUITING

Walnuts as an Infant Solid Food for Health

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective is to investigate the effect of walnuts on gut microbiota, inflammatory markers, atopic dermatitis status, and indices of allergy outcomes in breastfed infants during early complementary feeding. The three primary aims include: Aim 1: Evaluate the effect of walnut consumption on gut microbiota structure and function, inflammation, atopic dermatitis, and allergy outcomes. Aim 2: Evaluate the impact of walnut consumption on infant growth trajectories and risk of overweight. Aim 3 (exploratory): Identify walnut-specific food signatures that are associated with gut microbiota and immunity biomarkers using a novel nutri-metabolomics technique.

Official Title

Walnut as a First Food During Complementary Feeding on Gut Microbiota and Immunity Development in Breastfed Infants

Quick Facts

Study Start:2025-05-18
Study Completion:2027-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07081698

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:5 Months to 5 Months
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Full term: gestational age ≥ 37 weeks
  2. * Generally healthy without conditions that would affect normal growth
  3. * No significant consumption of complementary food (e.g., no more than 1 oz of solid foods per week)
  4. * Exclusively breastfed (\< 2 weeks of cumulative formula exposure)
  1. * Adults unable to consent
  2. * Pregnant women
  3. * Prisoners

Contacts and Locations

Study Contact

Nathan Campbell, MS
CONTACT
7655436716
Nathan.Campbell@colostate.edu
Kinzie Matzeller, MS RDNCLC
CONTACT
kinzie.matzeller@colostate.edu

Principal Investigator

Minghua Tang, Phd
PRINCIPAL_INVESTIGATOR
Colorado State University

Study Locations (Sites)

Food Science and Human Nutrition Clinical Research Laboratory
Fort Collins, Colorado, 80523
United States

Collaborators and Investigators

Sponsor: Colorado State University

  • Minghua Tang, Phd, PRINCIPAL_INVESTIGATOR, Colorado State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-18
Study Completion Date2027-12-31

Study Record Updates

Study Start Date2025-05-18
Study Completion Date2027-12-31

Terms related to this study

Keywords Provided by Researchers

  • Walnut
  • Microbiome
  • Infant
  • Pediatric
  • Nutrition
  • Health

Additional Relevant MeSH Terms

  • Gut -Microbiota
  • Inflammatory Markers
  • Infant Development