Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

Description

The purpose of this study is to see what effects, good and/or bad, proton radiation, and/or conventional radiation and hormonal therapy (if applicable), has on prostate cancer that has already returned or the risk of prostate cancer returning.

Conditions

Prostate Cancer

Talk to us

Study Overview

On this page

Study Details

Study overview

The purpose of this study is to see what effects, good and/or bad, proton radiation, and/or conventional radiation and hormonal therapy (if applicable), has on prostate cancer that has already returned or the risk of prostate cancer returning.

Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy

Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

Condition
Prostate Cancer
Intervention / Treatment

-

Contacts and Locations

Jacksonville

University of Florida Proton Therapy Institute, Jacksonville, Florida, United States, 32206

Warrenville

Northwestern Medicine Chicago Proton Center, Warrenville, Illinois, United States, 60555

Fairfax

Inova Schar Cancer Institute, Fairfax, Virginia, United States, 22031

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Prostate cancer treated primarily with open, laparoscopic or robotically assisted prostatectomy.
  • * Maximum PSA value of 20 ng/ml.
  • * Evidence of distant metastasis (M1).
  • * Prior systemic chemotherapy for any reason.
  • * Previous irradiation to the pelvis that would compromise the ability to deliver the prescribed study treatment.
  • * Active inflammatory bowel disease (Crohn's disease, diverticulitis or ulcerative colitis) affecting the rectum. (Non-active diverticulitis and Crohn's disease not affecting the rectum are allowed).
  • * History of hip replacement.
  • * Prior or concurrent cancer, other than non-melanomatous skin cancer, unless disease free for at least 5 years.
  • * Taking Saw Palmetto or methotrexate and unable or unwilling to discontinue its use during radiation.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Proton Collaborative Group,

Randal H Henderson, MD, PRINCIPAL_INVESTIGATOR, University of Florida Proton Therapy Institute

Study Record Dates

2050-08