Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children

Description

This study evaluates the effects of either Pediasure or Nourish formulas on the gastrointestinal microbiome in critically-ill children. Patients will be randomized to received either Pediasure or Nourish.

Conditions

Critical Illness, Dysbiosis, Pediatric ALL

Talk to us

Study Overview

On this page

Study Details

Study overview

This study evaluates the effects of either Pediasure or Nourish formulas on the gastrointestinal microbiome in critically-ill children. Patients will be randomized to received either Pediasure or Nourish.

Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children

Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children

Condition
Critical Illness
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States, 15224

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Admitted to the pediatric intensive care unit
  • * Age 1-17 years old
  • * Previously placed enteric tube designed for enteric feeding
  • * Vasoactive medication use
  • * History of allergies or intolerances to either Pediasure or Nourish
  • * Whey allergy or intolerance
  • * Gluten sensitivity or intolerance
  • * Medical condition that necessitate the use of specific formulas and/or nutritional needs (e.g. epilepsy requiring ketogenic diet, genetic metabolic dysfunction with specific formula requirements)

Ages Eligible for Study

1 Year to 17 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pittsburgh,

Raj Aneja, MD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh Medical Center

Study Record Dates

2025-08