RECRUITING

PET/MRI in the Diagnosis of Chronic Pain

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain. Using \[18F\]-FTC-146 and positron emission tomography/magnetic resonance imaging (PET/MRI), the investigators hope to identify the source of pain generation in patients with chronic pain. The purpose of this study is to compare the uptake of \[18F\]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain.

Official Title

Use of [18F]FTC-146 PET/MRI in the Diagnosis of Chronic Pain

Quick Facts

Study Start:2018-07-16
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03556137

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. At least 18 years old.
  2. 2. Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan.
  3. 1. At least 18 years old.
  4. 2. Chronic pain (nociceptive, neuropathic or mixed pain) lasting greater than 2 months.
  5. 3. Pain level of at least 4/10 on a 0-10 Comparative Pain Scale.
  6. 4. Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan.
  1. 1. Pain
  2. 2. Pain Medication
  3. 3. MRI incompatible
  4. 4. Pregnant or nursing
  5. 5. Non-English speaker
  6. 6. Claustrophobic
  7. 1. MRI incompatible
  8. 2. Pregnant or nursing
  9. 3. Non-English speaker
  10. 4. Claustrophobic

Contacts and Locations

Study Contact

Anand Veeravagu, MD
CONTACT
(650) 498-6154
anand.veeravagu@stanford.edu
Adrian Valladarez
CONTACT
adrian98@stanford.edu

Principal Investigator

Anand Veeravagu, MD
PRINCIPAL_INVESTIGATOR
Stanford University Department of Neurosurgery

Study Locations (Sites)

Stanford University
Stanford, California, 94305
United States

Collaborators and Investigators

Sponsor: Stanford University

  • Anand Veeravagu, MD, PRINCIPAL_INVESTIGATOR, Stanford University Department of Neurosurgery

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-07-16
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2018-07-16
Study Completion Date2024-12-31

Terms related to this study

Keywords Provided by Researchers

  • PET/MRI
  • Chronic Pain

Additional Relevant MeSH Terms

  • Neuropathic Pain
  • Nociceptive Pain
  • Mixed Pain (Nociceptive and Neuropathic)
  • Spinal Pain
  • Radiculopathy
  • Myelopathy
  • Neurogenic Claudication