RECRUITING

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes. This project is translational and has the potential to lead to future translational research opportunities, including interventional trials in which therapeutic escalation is offered at the early circulating tumor DNA (ctDNA) molecular residual disease (MRD) detection timepoint. Ultimately, the integration of ctDNA into the clinical workflow has the potential to enhance cancer diagnosis, treatment, surveillance, and prognosis, and guide clinical decision-making in this era of personalized precision medicine.

Official Title

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Quick Facts

Study Start:2019-05-29
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04354064

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Eligible healthy donors will be at least 18 years of age.
  1. * Healthy donors younger than 18 years of age

Contacts and Locations

Study Contact

Russell Pachynski, M.D.
CONTACT
314-286-2341
rkpachynski@wustl.edu

Principal Investigator

Russell Pachynski, M.D.
PRINCIPAL_INVESTIGATOR
Washington University School of Medicine

Study Locations (Sites)

Washington University School of Medicine
Saint Louis, Missouri, 63110
United States

Collaborators and Investigators

Sponsor: Washington University School of Medicine

  • Russell Pachynski, M.D., PRINCIPAL_INVESTIGATOR, Washington University School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-05-29
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2019-05-29
Study Completion Date2025-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Healthy Volunteer
  • Prostate Cancer
  • Head and Neck Cancer
  • Esophageal Cancer
  • Genitourinary Cancer
  • Sarcoma
  • Breast Cancer
  • Colon Cancer
  • Gastrointestinal Cancer
  • Solid Tumor Cancer
  • Lung Cancer
  • Skin Cancer
  • Melanoma