A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

Description

ATLAS-101 is a Phase I/II clinical trial of AMXI-5001 in adult participants with advanced malignancies who have previously failed other therapies. The study has two phases. The purpose of Phase I (Dose Escalation) is to confirm the appropriate treatment dose and Phase II (Dose Expansion) is to characterize the safety and efficacy of AMXI-5001.

Conditions

Advanced Malignant Neoplasm, Breast Cancer, Ovarian Cancer, Homologous Recombination Deficiency, Prostate Cancer, Pancreatic Cancer

Study Overview

Study Details

Study overview

ATLAS-101 is a Phase I/II clinical trial of AMXI-5001 in adult participants with advanced malignancies who have previously failed other therapies. The study has two phases. The purpose of Phase I (Dose Escalation) is to confirm the appropriate treatment dose and Phase II (Dose Expansion) is to characterize the safety and efficacy of AMXI-5001.

A Phase I/II, Open Label, Multi-center, Non-randomized Dose Escalation and Dose Expansion Study of AMXI-5001 in Patients With Advanced Malignancies

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

Condition
Advanced Malignant Neoplasm
Intervention / Treatment

-

Contacts and Locations

Los Angeles

University of California, Los Angles (UCLA) Department of Medicine - Hematology/Oncology, Los Angeles, California, United States, 90404

Tampa

Moffitt Cancer Center and Research Institute, Tampa, Florida, United States, 33612

Baltimore

Johns Hopkins, Baltimore, Maryland, United States, 21218

Nashville

SCRI Oncology Partners, Nashville, Tennessee, United States, 37203

Houston

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    AtlasMedx, Incorporated,

    Pamela Munster, MD, STUDY_DIRECTOR, AtlasMedx, Incorporated

    Study Record Dates

    2026-10