Understanding Motivation in Parkinson's Patients Through Neurophysiology

Description

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.

Conditions

Parkinson Disease, Deep Brain Stimulation, Motivation

Study Overview

Study Details

Study overview

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.

Understanding Motivation in Parkinson's Patients Through Neurophysiology

Understanding Motivation in Parkinson's Patients Through Neurophysiology

Condition
Parkinson Disease
Intervention / Treatment

-

Contacts and Locations

San Francisco

University of California San Francisco, San Francisco, California, United States, 94158

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Has Parkinson's Disease or Dystonia
  • * Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN
  • * Has DBS device implanted either bilaterally or unilaterally
  • * Male or female
  • * More than 1 month post-DBS surgery
  • * Severe cognitive impairments
  • * Has MOCA score below 20
  • * Pregnancy
  • * Age less than 18 years old

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of California, San Francisco,

Simon J Little, MBBS, PhD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

2030-12-01