RECRUITING

Biomarker of Diabetic Retinopathy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.

Official Title

Biomarker of Diabetic Retinopathy

Quick Facts

Study Start:2022-01-01
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05079399

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ability to cooperate with imaging procedures.
  2. * Health status: established type 2 diabetes
  3. * No history of panretinal photocoagulation (PRP)
  4. * No history of treatment with intravitreal agents for past 12 months
  1. * Previous or current malignancy
  2. * Acute or chronic infection (HIV, hepatitis B or C, tuberculosis)
  3. * Cerebral vascular accident or cerebral vascular procedure
  4. * Current pregnancy
  5. * History of organ transplantation
  6. * Presence of a graft (to avoid any effect of the graft)
  7. * History of previous vitrectomy
  8. * Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.

Contacts and Locations

Study Contact

Ashay D Bhatwadekar, PhD, RPh
CONTACT
3172785075
abhatwad@iupui.edu
Amir R Hajrasouliha, MD
CONTACT
3179441154
amhajras@iu.edu

Study Locations (Sites)

Spring Mill Clinic
Carmel, Indiana, 46920
United States
Eskenazi Eye Clinic
Indianapolis, Indiana, 46202
United States
Glick Eye Institute
Indianapolis, Indiana, 46202
United States

Collaborators and Investigators

Sponsor: Indiana University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-01-01
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2022-01-01
Study Completion Date2026-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Diabetic Retinopathy