Biomarker of Diabetic Retinopathy

Description

Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.

Conditions

Diabetic Retinopathy

Study Overview

Study Details

Study overview

Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.

Biomarker of Diabetic Retinopathy

Biomarker of Diabetic Retinopathy

Condition
Diabetic Retinopathy
Intervention / Treatment

-

Contacts and Locations

Carmel

Spring Mill Clinic, Carmel, Indiana, United States, 46920

Indianapolis

Eskenazi Eye Clinic, Indianapolis, Indiana, United States, 46202

Indianapolis

Glick Eye Institute, Indianapolis, Indiana, United States, 46202

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Ability to cooperate with imaging procedures.
  • * Health status: established type 2 diabetes
  • * No history of panretinal photocoagulation (PRP)
  • * No history of treatment with intravitreal agents for past 12 months
  • * Previous or current malignancy
  • * Acute or chronic infection (HIV, hepatitis B or C, tuberculosis)
  • * Cerebral vascular accident or cerebral vascular procedure
  • * Current pregnancy
  • * History of organ transplantation
  • * Presence of a graft (to avoid any effect of the graft)
  • * History of previous vitrectomy
  • * Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Indiana University,

Study Record Dates

2026-06-30