RECRUITING

Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goals of this project are 1) to determine the incidence of neurological voice disorders in patients with dystonia and essential tremor undergoing deep brain stimulation (DBS), 2) investigate the neuroimaging and intracranial neurophysiology correlates of voice dysfunction in these subjects, and subsequently 3) determine the effects of DBS on voice function.

Official Title

Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor

Quick Facts

Study Start:2022-06-21
Study Completion:2026-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05150093

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Kristina Simonyan, MD, PhD
CONTACT
617-573-6016
simonyan_lab@meei.harvard.edu

Principal Investigator

Kristina Simonyan, MD, PhD
STUDY_DIRECTOR
Massachusetts Eye and Ear

Study Locations (Sites)

Massachusetts General Hospital, University of California San Francisco, University of Utah
Boston, Massachusetts, 02114
United States

Collaborators and Investigators

Sponsor: Massachusetts Eye and Ear Infirmary

  • Kristina Simonyan, MD, PhD, STUDY_DIRECTOR, Massachusetts Eye and Ear

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-06-21
Study Completion Date2026-08-31

Study Record Updates

Study Start Date2022-06-21
Study Completion Date2026-08-31

Terms related to this study

Additional Relevant MeSH Terms

  • Laryngeal Dystonia
  • Spasmodic Dysphonia
  • Tremor
  • Dystonia