RECRUITING

Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This clinical trial evaluates deoxyribonucleic acid (DNA) methylation signatures in diagnosing and managing thyroid nodules. The purpose of this research is to develop a new test for thyroid cancer. This test will use needle biopsies (small collections of tissue with a needle) from the thyroid to determine whether the participant has a malignant (cancer) or benign (not showing cancer) thyroid tumor. The information learned from this trial may help develop a more accurate test so that patients do not have unnecessary surgeries for nodules that are thought to be suspicious but are actually benign.

Official Title

Evaluation of DNA Methylation Signatures in Diagnosis and Management of Thyroid Nodules

Quick Facts

Study Start:2021-10-22
Study Completion:2026-10-22
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05229341

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients without impaired decision-making capacity and who are undergoing needle biopsies for thyroid nodule diagnosis
  2. * Over the age of 18
  3. * Any gender, race and ethnicity
  4. * Patients must provide informed consent prior to use of their tissues and clinical data
  1. * Children are excluded from the study, since the biology of children thyroid nodules is different from adults

Contacts and Locations

Principal Investigator

John H Yim
PRINCIPAL_INVESTIGATOR
City of Hope Medical Center

Study Locations (Sites)

City of Hope Medical Center
Duarte, California, 91010
United States

Collaborators and Investigators

Sponsor: City of Hope Medical Center

  • John H Yim, PRINCIPAL_INVESTIGATOR, City of Hope Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-10-22
Study Completion Date2026-10-22

Study Record Updates

Study Start Date2021-10-22
Study Completion Date2026-10-22

Terms related to this study

Additional Relevant MeSH Terms

  • Thyroid Gland Carcinoma