Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

Description

To determine whether using bpMRI in subjects who are at high risk of developing prostate cancer in conjunction with PSA will improve prostate cancer screening protocols.

Conditions

Prostate Cancer, Magnetic Resonance Imaging, Population at Risk

Talk to us

Study Overview

On this page

Study Details

Study overview

To determine whether using bpMRI in subjects who are at high risk of developing prostate cancer in conjunction with PSA will improve prostate cancer screening protocols.

Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

Condition
Prostate Cancer
Intervention / Treatment

-

Contacts and Locations

Lake Success

Cynthia Knauer, Lake Success, New York, United States, 11042

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. PSA between 1.0 and 2.5 ng/dL
  • 2. High risk for prostate cancer, i.e. Black or they have a first degree relative with history of prostate cancer (father, brother) or specific genetic syndromes i.e. BRCA 1/2, HOX B13, Lynch syndrome, ATM, CHEK2
  • 3. Patient is willing to participated in prostate cancer screening
  • 4. Patient is capable of giving informed consent
  • 1. Nodularity or firmness of prostate on exam
  • 2. Patient has undergone a prior biopsy or prostate surgery
  • 3. Patient is taking 5-alpha reductase inhibitors to manage benign prostatic hyperplasia, as this can significantly alter PSA levels.
  • 4. Patient has a history of UTI or prostatitis in the preceding 6 months, as this can significantly alter PSA levels.
  • 5. Patient has a contraindication to MRI, these include but are not limited to pacemakers, neurostimulator devices, metal cardiac valves, certain tattoos, or foreign bodies
  • 6. Participants that experience claustrophobia, anxiety and/or vertigo when moved inside the scanner
  • 7. The participant cannot tolerate lying flat for the study duration

Ages Eligible for Study

40 Years to 55 Years

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Northwell Health,

Ardeshir Rastinehad, DO, PRINCIPAL_INVESTIGATOR, Northwell Health

Manish Vira, MD, PRINCIPAL_INVESTIGATOR, Northwell Health

Study Record Dates

2026-10-31