RECRUITING

The Effect of Sleep Loss on Emotion Regulation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and control. The investigators will address and attempt to answer two questions. (i) How do three nights of reduced sleep or a diagnosis of Insomnia Disorder affect the processing and regulation of emotional information compared to typical, undisturbed sleep? (ii) What overlapping and distinct neural mechanisms are engaged and associated with behavioral effects when attempting to process and regulate emotions in a sleep restricted state or with a clinical diagnosis of Insomnia Disorder? This study will investigate sleep's role in emotion processing and regulation. The findings will help further understanding of the role of sleep in healthy emotional functioning.

Official Title

The Impact of Insufficient Sleep and Insomnia Disorder on Behavioral and Neural Markers of Emotion Regulation

Quick Facts

Study Start:2023-05-11
Study Completion:2027-07-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05393830

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * willing and able to follow the protocol
  2. * willing and able to meet inclusion criteria for fMRI scanning
  3. * willing to refrain from alcohol and recreational drugs for the duration of the protocol
  4. * normal or corrected to normal vision is required
  1. * left-handedness or ambidexterity
  2. * the use of any drugs that could affect either sleep or cognitive functioning (e.g., prescription sleeping pills or antidepressants)

Contacts and Locations

Study Contact

Tony J Cunningham, PhD
CONTACT
617-667-3337
acunnin4@BIDMC.Harvard.edu

Principal Investigator

Janet M Mullington, PhD
PRINCIPAL_INVESTIGATOR
Beth Israel Deaconess Medical Center

Study Locations (Sites)

Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215
United States

Collaborators and Investigators

Sponsor: Beth Israel Deaconess Medical Center

  • Janet M Mullington, PhD, PRINCIPAL_INVESTIGATOR, Beth Israel Deaconess Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-05-11
Study Completion Date2027-07-31

Study Record Updates

Study Start Date2023-05-11
Study Completion Date2027-07-31

Terms related to this study

Keywords Provided by Researchers

  • Emotion
  • Sleep Restriction
  • Insomnia Disorder
  • Sleep
  • Emotion Regulation
  • functional Magnetic Resonance Imaging (fMRI)

Additional Relevant MeSH Terms

  • Sleep
  • Insomnia
  • Sleep Deprivation