RECRUITING

Inhaled Isopropyl Alcohol for Treatment of Nausea

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.

Official Title

Inhaled Isopropyl Alcohol for the Treatment of Nausea in a Pediatric Emergency Department: A Open Label, Randomized Controlled Clinical Trial

Quick Facts

Study Start:2022-04-20
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05418244

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:7 Years to 17 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Patients with a chief complaint of nausea or vomiting
  2. * Ages 7-178 years, both sexes
  3. * Weight ≥ 15 kg
  4. * Baxter Animated Retching Faces (BARF) nausea severity score ≥ 4/10
  1. * 1. Require IV access
  2. * Inability to breathe in/out through the nose
  3. * Anosmia (self- or parental report)
  4. * Allergy to isopropyl alcohol or ondansetron
  5. * Current or history of alcohol abuse
  6. * Inability to communicate feeling nauseous
  7. * Inability to follow directions regarding taking deep breaths through the nose
  8. * Known prolonged QT interval
  9. * Pregnancy
  10. * Received antiemetics within the last 8 hours
  11. * Currently taking apomorphine

Contacts and Locations

Study Contact

Haiping Qiao, MBBS, MS
CONTACT
7163230055
hqiao@upa.chob.edu
Alana Koehler, MD
CONTACT
315576264
alanakoe@buffalo.edu

Principal Investigator

Alana Koehler, MD
PRINCIPAL_INVESTIGATOR
SUNY Buffalo
Heather Territo, MD
STUDY_DIRECTOR
SUNY Buffalo

Study Locations (Sites)

Oishei Children's Hospital
Buffalo, New York, 14203
United States

Collaborators and Investigators

Sponsor: State University of New York at Buffalo

  • Alana Koehler, MD, PRINCIPAL_INVESTIGATOR, SUNY Buffalo
  • Heather Territo, MD, STUDY_DIRECTOR, SUNY Buffalo

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-20
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2022-04-20
Study Completion Date2025-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Vomiting
  • Nausea
  • Children, Only