RECRUITING

Micro-UltraSound In Cancer - Active Surveillance

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, finishing with 12 systematic biopsy cores. The primary goal is to compare microUS to MRI for the detection of ≥GG2 PCa at confirmatory biopsy. This study will also collect blood samples from participants to be used for future biomarker studies.

Official Title

Micro-UltraSound In Cancer - Active Surveillance (MUSIC-AS)

Quick Facts

Study Start:2023-01-01
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05558241

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult men with Gleason Grade Group 1 prostate cancer managed by active surveillance who require a confirmatory prostate biopsy
  1. * Men who cannot undergo a prostate MRI
  2. * Men who cannot undergo a prostate biopsy

Contacts and Locations

Study Contact

Adam Kinnaird, MD, PhD
CONTACT
780-407-5800
ask@ualberta.ca
Stacey Broomfield, PhD
CONTACT
780-407-5800
sbroomfi@ualberta.ca

Principal Investigator

Adam Kinnaird, MD, PhD
PRINCIPAL_INVESTIGATOR
University of Alberta

Study Locations (Sites)

University of California Los Angeles, Department of Urology
Los Angeles, California, 90095
United States

Collaborators and Investigators

Sponsor: University of Alberta

  • Adam Kinnaird, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Alberta

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-01
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2023-01-01
Study Completion Date2026-06-30

Terms related to this study

Keywords Provided by Researchers

  • Active surveillance
  • micro-ultrasound

Additional Relevant MeSH Terms

  • Prostate Cancer