Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst

Description

This study will help us better understand how the brain works in people with Parkinson's disease (PD). PD is a brain disease that gets worse over time, and affects over 10 million people world-wide. A common treatment for PD is Deep Brain Stimulation (DBS). To improve DBS therapy for PD, we need a deeper understanding of how the different parts of the brain work together in PD, and how this relates to movement and thinking problems that people with PD experience. We may be able to use the results of this study to improve DBS treatments in the future.

Conditions

Parkinson Disease

Study Overview

Study Details

Study overview

This study will help us better understand how the brain works in people with Parkinson's disease (PD). PD is a brain disease that gets worse over time, and affects over 10 million people world-wide. A common treatment for PD is Deep Brain Stimulation (DBS). To improve DBS therapy for PD, we need a deeper understanding of how the different parts of the brain work together in PD, and how this relates to movement and thinking problems that people with PD experience. We may be able to use the results of this study to improve DBS treatments in the future.

Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst

Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst

Condition
Parkinson Disease
Intervention / Treatment

-

Contacts and Locations

Minneapolis

University Of Minnesota, Minneapolis, Minnesota, United States, 55445

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of idiopathic PD
  • * Surgery at UMN to implant DBS system with directional lead(s) and multiple independent current control IPG is planned as part of routine clinical care
  • * At least 21 years old
  • * Existing or planned 7T brain imagery
  • * Other significant neurological disorder
  • * History of dementia
  • * Patients with post-operative complications or adverse effects (e.g. ON stimulation dystonias) that affect patient safety or confound the experiment will be excluded from further study
  • * Pregnant women
  • * Known radiation exposure within the last year that is determined to be unsafe when compounded with the expected radiation dose from intraoperative fluoroscopy to place ECoG strip

Ages Eligible for Study

21 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Minnesota,

Study Record Dates

2027-03-01