ACTIVE_NOT_RECRUITING

A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer

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Conditions

Prostate CancerProstate AdenocarcinomaLocalized Prostate Carcinomaexercise therapyMemorial Sloan Kettering Cancer Center22-419

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to find out the effects of exercise therapy on indicators of prostate cancer in people with low-risk prostate cancer who are on active surveillance. The exercise therapy in this study will be regular home-based walking sessions on a treadmill, and that therapy will be assigned by an exercise physiologist (a medical professional who studies how exercise affects the human body). Some participants in this study will have the assigned exercise therapy, and some participants will participate in their usual exercise routines. Researchers will compare how the assigned exercise therapy and the usual exercise routines affect indicators of prostate cancer in participants. This study will not provide treatment for prostate cancer.

Official Title

Phase 2 Trial of Exercise Therapy on Markers of Progression in Localized Prostate Cancer

Quick Facts

Study Start:2023-02-10
Study Completion:2027-02-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05751434

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age ≥ 18
  2. * Men with histologically confirmed localized prostate cancer undergoing active surveillance.
  3. * Inactive, defined as not meeting the national exercise guidelines for cancer patients (\<150 minutes/week of moderate or vigorous exercise)43 as assessed by remote activity and heart rate tracking for a 7-day period prior to study entry (general physical activity screening assessment via smart watch).
  4. * Screening clearance by an MSK Exercise Physiologist (i.e., review of ECG)
  5. * BMI \<40 kg/m\^2
  6. * Cleared for exercise participation as per pre-screening clearance via the Physical Activity Readiness Questionnaire (PAR-Q+) (Appendix B)
  1. * Enrollment in any other program that may alter the impact of exercise on tumor outcomes (e.g., weight loss program)
  2. * Any neoadjuvant anticancer treatment of any kind for prostate cancer in the last 5 years
  3. * Any history of systemic anticancer therapy in the last 15 years
  4. * Distant metastatic malignancy of any kind
  5. * Any other condition or intercurrent illness that, in the opinion of the investigator, makes the subject a poor candidate for study participation

Contacts and Locations

Principal Investigator

Jessica Scott, PhD
PRINCIPAL_INVESTIGATOR
Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

University of California, Los Angeles (Data and Specimen Analysis Only)
Los Angeles, California, 90095-1781
United States
Hartford Healthcare Alliance (Data collection only)
Hartford, Connecticut, 06102
United States
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, 07920
United States
Memorial Sloan Kettering Monmouth (Limited protocol activities)
Middletown, New Jersey, 07748
United States
Memorial Sloan Kettering Bergen (Limited protocol activities)
Montvale, New Jersey, 07645
United States
Memorial Sloan Kettering Suffolk - Commack (Limited protocol activities)
Commack, New York, 11725
United States
Memorial Sloan Kettering Westchester (Limited protocol activities)
Harrison, New York, 10604
United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065
United States
Memorial Sloan Kettering Nassau (Limited protocol activites)
Rockville Centre, New York, 11553
United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

  • Jessica Scott, PhD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-02-10
Study Completion Date2027-02-10

Study Record Updates

Study Start Date2023-02-10
Study Completion Date2027-02-10

Terms related to this study

Keywords Provided by Researchers

  • Prostate Cancer
  • Prostate Adenocarcinoma
  • Localized Prostate Carcinoma
  • exercise therapy
  • Memorial Sloan Kettering Cancer Center
  • 22-419

Additional Relevant MeSH Terms

  • Prostate Cancer
  • Prostate Adenocarcinoma
  • Localized Prostate Carcinoma