Circadian Intervention to Improve Cardiometabolic Health

Description

The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD). Participants will undergo a randomized controlled trial, with circadian intervention and control (healthy lifestyle) groups. The circadian intervention is designed to reduce nighttime light exposure and after-dinner snack food intake. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).

Conditions

Cardiometabolic Syndrome, Type 2 Diabetes, Sleep, Time Restricted Feeding, Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit, Sleep Hygiene

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Study Overview

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Study Details

Study overview

The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD). Participants will undergo a randomized controlled trial, with circadian intervention and control (healthy lifestyle) groups. The circadian intervention is designed to reduce nighttime light exposure and after-dinner snack food intake. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).

Timing of Circadian Synchronizers: The TOCS Study

Circadian Intervention to Improve Cardiometabolic Health

Condition
Cardiometabolic Syndrome
Intervention / Treatment

-

Contacts and Locations

Salt Lake City

College of Health Research Complex--University of Utah, Salt Lake City, Utah, United States, 84112

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age: 18-45 years old; equal numbers of men and women
  • 2. Body mass index (BMI): 25.0-34.9 kg/m2,
  • 3. Sleep Habits: habitual self-reported average total sleep time (TST) \<6.5 hours per night for prior 6 months
  • 1. Clinically diagnosed sleep disorder or major psychiatric illness
  • 2. Evidence of significant organ dysfunction or disease (e.g., diagnosed diabetes, cardiovascular disease, or kidney disease)
  • 3. Use of prescription drugs or substances known to influence sleep or glucose metabolism
  • 4. Shift-work: current or history of within last year
  • 5. Weight change: \>10% of body weight over prior six months
  • 6. Experiencing menopause or post-menopausal
  • 7. Current enrollment in weight loss or physical activity program like the Diabetes Prevention Program
  • 8. Currently pregnant or planning to become pregnant, or currently lactating.
  • 9. Currently smoking
  • 10. Alcohol intake \>3 drinks per day or \>14 drinks per week

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Utah,

Study Record Dates

2026-03