RECRUITING

A Registry for People With T-cell Lymphoma

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Conditions

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic LeukemiaT-cell Large Granular Lymphocytic LeukemiaChronic Lymphoproliferative Disorder of NK CellsAggressive NK-cell LeukemiaSystemic Epstein-Barr Virus Positive T-Cell Lymphoproliferative Disease of Childhood (Disorder)Systemic Epstein Barr Virus Positive T-Cell Lymphoproliferative Disease of ChildhoodChronic Active EBV Infection of T-and NK-Cell Type, Systemic FormHydroa Vacciniforme-Like Lymphoproliferative DisorderAdult T-cell Leukemia/LymphomaExtranodal NK/T-cell Lymphoma, Nasal TypeEnteropathy-associated T-cell LymphomaMonomorphic Epitheliotropic Intestinal T-Cell LymphomaIntestinal T-Cell Lymphoma, Not Otherwise SpecifiedIndolent T-Cell Lymphoproliferative Disorder of the Gastrointestinal TractHepatosplenic T-cell LymphomaSubcutaneous Panniculitis-Like T-Cell LymphomaMycosis FungoidesSezary SyndromePrimary Cutaneous Anaplastic Large Cell LymphomaPrimary Cutaneous T-cell LymphomaPrimary Cutaneous CD8-Positive Aggressive Epidermotropic T-Cell LymphomaPrimary Cutaneous Acral CD8-Positive T-Cell LymphomaPeripheral T-Cell Lymphoma, Not Otherwise SpecifiedAngioimmunoblastic T-cell LymphomaFollicular T-Cell LymphomaNodal Peripheral T-Cell Lymphoma With TFH PhenotypeAnaplastic Large Cell Lymphoma, ALK-PositiveAnaplastic Large Cell Lymphoma, ALK-negativeBreast Implant-Associated Anaplastic Large Cell Lymphoma23-190Memorial Sloan Kettering Cancer CenterT-cell Lymphoma Master RepositoryTCLMR

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this registry study is to create a database-a collection of information-for better understanding T-cell lymphoma. Researchers will use the information from this database to learn more about how to improve outcomes for people with T-cell lymphoma.

Official Title

The T-cell Lymphoma Master Repository (TCLMR): A Prospective Databank of Patients With T-cell Lymphoma With Clinical Annotation and Matched Tumor Specimens

Quick Facts

Study Start:2023-07-27
Study Completion:2030-07-27
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05978141

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Written informed consent
  2. * Adequate fresh or archival tumor biopsy or intent to obtain fresh tumor biopsy.
  3. * Pathologically-confirmed mature T- or natural killer (NK)-cell lymphoma meeting one of the following diagnostic criterion (based on WHO classification and NCCN guidelines):
  4. * T-cell prolymphocytic leukemia
  5. * T-cell large granular lymphocytic leukemia
  6. * Chronic lymphoproliferative disorder of NK cells
  7. * Aggressive NK-cell leukemia
  8. * Systemic Epstein-Barr virus (EBV)-positive T-cell lymphoma of childhood
  9. * Chronic active EBV infection of T- and NK-cell type, systemic form
  10. * Hydroa vacciniforme-like lymphoproliferative disorder
  11. * Adult T-cell leukemia/lymphoma
  12. * Extranodal NK/T-cell lymphoma, nasal type
  13. * Enteropathy-associated T-cell lymphoma
  14. * Monomorphic epitheliotropic intestinal T-cell lymphoma
  15. * Intestinal T-cell lymphoma, not otherwise specified (NOS)
  16. * Indolent T-cell lymphoproliferative disorder of the gastrointestinal tract
  17. * Hepatosplenic T-cell lymphoma
  18. * Subcutaneous panniculitis-like T-cell lymphoma
  19. * Mycosis fungoides (limited to those with ≥ stage IB disease and those receiving active therapy)
  20. * Sézary syndrome
  21. * Primary cutaneous anaplastic large cell lymphoma (receiving systemic therapy)
  22. * Primary cutaneous Gamma-Delta T-cell lymphoma
  23. * Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma
  24. * Primary cutaneous acral CD8+ T-cell lymphoma (receiving systemic therapy)
  25. * Peripheral T-cell lymphoma, not otherwise specified
  26. * Angioimmunoblastic T-cell lymphoma
  27. * Follicular T-cell lymphoma
  28. * Nodal peripheral T-cell lymphoma with TFH phenotype
  29. * Anaplastic large cell lymphoma, ALK-positive
  30. * Anaplastic large cell lymphoma, ALK-negative
  31. * Breast-implant associated anaplastic large cell lymphoma.
  32. * NOTE: Patients with diagnoses of mycosis fungoides, primary cutaneous anaplastic large cell lymphoma, and/or primary cutaneous acral CD8+ T-cell lymphoma must be receiving systemic therapy.
  1. * Patients with of mycosis fungoides, primary cutaneous anaplastic large cell lymphoma, and/or primary cutaneous acral CD8+ T-cell lymphoma not receiving systemic therapy.
  2. * Inability to collect prospective data, measure response, or perform adequate follow-up assessments in the clinical judgment of the treating physician. NOTE: Repository participation does not exclude participation in clinical trials, nor does existing clinical trial participation exclude enrollment in the study herein outlined.

Contacts and Locations

Study Contact

Steven Horwitz, MD
CONTACT
646-608-2680
horwitzs@MSKCC.ORG
Alison Moskowitz, MD
CONTACT
646-608-3726
moskowia@mskcc.org

Principal Investigator

Steven Horwitz, MD
PRINCIPAL_INVESTIGATOR
Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

City of Hope Cancer Center (Data collection only)
Duarte, California, 91010
United States
UNIVERSITY OF CALIFORNIA SAN DIEGO (Data collection only)
San Diego, California, 92103
United States
University of California San Francisco (Data collection only)
San Francisco, California, 94143
United States
Stanford University Medical Center (Data collection only)
Stanford, California, 94305-5408
United States
University of Colorado (Data Collection Only)
Aurora, Colorado, 80045
United States
Yale University (Data Collection Only)
New Haven, Connecticut, 06511
United States
University of Miami (Data Collection Only)
Miami, Florida, 33136
United States
Moffitt Cancer Center (Data Collection Only)
Tampa, Florida, 33612
United States
Emory University (Data Collection Only)
Atlanta, Georgia, 30322
United States
Northwestern Medicine (Data Collection)
Chicago, Illinois, 60611
United States
Massachusetts General Hospital (Data Collection Only)
Boston, Massachusetts, 02114
United States
Dana Farber Cancer Institute (Data Collection Only)
Boston, Massachusetts, 02115
United States
Mayo Clinic (Data Collection Only)
Rochester, Minnesota, 55905
United States
Washington University (Data Collection Only)
Saint Louis, Missouri, 63110
United States
University of Nebraska (Data collection only)
Omaha, Nebraska, 68198-7680
United States
Memorial Sloan Kettering at Basking Ridge (All protocol activities)
Basking Ridge, New Jersey, 07920
United States
Memorial Sloan Kettering Monmouth (All protocol activities)
Middletown, New Jersey, 07748
United States
Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (All protocol activities)
Commack, New York, 11725
United States
Memorial Sloan Kettering Westchester (All protocol activities)
Harrison, New York, 10604
United States
Weill Cornell Medical Center (Data Collection Only)
New York, New York, 10021
United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065
United States
Memorial Sloan Kettering Nassau (All protocol activities)
Uniondale, New York, 11553
United States
Ohio State University (Data Collection Only)
Columbus, Ohio, 43210
United States
University of Pennsylvania (Data Collection Only)
Philadelphia, Pennsylvania, 19104
United States
Thomas Jefferson University Hospital (Data collection only)
Philadelphia, Pennsylvania, 19107
United States
MD Anderson Cancer Center (Data Collection Only)
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

  • Steven Horwitz, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-27
Study Completion Date2030-07-27

Study Record Updates

Study Start Date2023-07-27
Study Completion Date2030-07-27

Terms related to this study

Keywords Provided by Researchers

  • 23-190
  • T-cell lymphoma
  • Memorial Sloan Kettering Cancer Center
  • T-cell Lymphoma Master Repository
  • TCLMR

Additional Relevant MeSH Terms

  • T-cell Lymphoma
  • NK-Cell Lymphoma
  • T-cell Prolymphocytic Leukemia
  • T-cell Large Granular Lymphocytic Leukemia
  • Chronic Lymphoproliferative Disorder of NK Cells
  • Aggressive NK-cell Leukemia
  • Systemic Epstein-Barr Virus Positive T-Cell Lymphoproliferative Disease of Childhood (Disorder)
  • Systemic Epstein Barr Virus Positive T-Cell Lymphoproliferative Disease of Childhood
  • Chronic Active EBV Infection of T-and NK-Cell Type, Systemic Form
  • Hydroa Vacciniforme-Like Lymphoproliferative Disorder
  • Adult T-cell Leukemia/Lymphoma
  • Extranodal NK/T-cell Lymphoma, Nasal Type
  • Enteropathy-associated T-cell Lymphoma
  • Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma
  • Intestinal T-Cell Lymphoma, Not Otherwise Specified
  • Indolent T-Cell Lymphoproliferative Disorder of the Gastrointestinal Tract
  • Hepatosplenic T-cell Lymphoma
  • Subcutaneous Panniculitis-Like T-Cell Lymphoma
  • Mycosis Fungoides
  • Sezary Syndrome
  • Primary Cutaneous Anaplastic Large Cell Lymphoma
  • Primary Cutaneous T-cell Lymphoma
  • Primary Cutaneous CD8-Positive Aggressive Epidermotropic T-Cell Lymphoma
  • Primary Cutaneous Acral CD8-Positive T-Cell Lymphoma
  • Peripheral T-Cell Lymphoma, Not Otherwise Specified
  • Angioimmunoblastic T-cell Lymphoma
  • Follicular T-Cell Lymphoma
  • Nodal Peripheral T-Cell Lymphoma With TFH Phenotype
  • Anaplastic Large Cell Lymphoma, ALK-Positive
  • Anaplastic Large Cell Lymphoma, ALK-negative
  • Breast Implant-Associated Anaplastic Large Cell Lymphoma