RECRUITING

Prostate-Specific Membrane Antigen (PSMA) Radionuclide Therapy

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is a single-center registry study collecting clinical data regarding the treatment of PSMA-positive metastatic castration-resistant prostate cancer treated with PSMA radionuclide therapy per the treating physician's discretion. Clinical data from candidates for or who undergo the PSMA procedure at Methodist Dallas Medical Center from August 2022 to August 2027 will be collected after discharge and patients will undergo clinical follow-up per the treating physician's discretion.

Official Title

Prostate-Specific Membrane Antigen (PSMA) Radionuclide Therapy for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Quick Facts

Study Start:2023-08-02
Study Completion:2024-08-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05995236

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 1. \>18 years of age
  2. * 2. Diagnosed with PSMA-positive metastatic castration-resistant prostate cancer and - has consented to undergo PSMA nuclear therapy per the treating physician. Specifically:
  3. * Metastatic or Locally Advanced AND Inoperable
  4. * Clear disease progression on PSMA-PET/CT
  5. * PSMA-PET/CT scan positive disease within 6 weeks
  6. * Labs:
  7. * Hemoglobin: \>8 g/dL
  8. * White blood cell count: \>2K cells/µL
  9. * Platelet (Thrombocyte) count: \>75 x 109/L
  10. * No prior therapy with Radium-223 Dichloride
  1. * Patients who do not meet the Inclusion Criteria laid out in section 4.2 will be excluded from the study.

Contacts and Locations

Study Contact

Kavya Vinod Mankulangara, PharmD
CONTACT
(214) 947-74604
clinicalresearch@mhd.com
Bethany Brauer, MPH
CONTACT
(214) 947-4459
clinicalresearch@mhd.com

Principal Investigator

Alexandru Bageac, MD
PRINCIPAL_INVESTIGATOR
Methodist Health System

Study Locations (Sites)

Methodist Dallas Medical Center
Dallas, Texas, 75203
United States

Collaborators and Investigators

Sponsor: Methodist Health System

  • Alexandru Bageac, MD, PRINCIPAL_INVESTIGATOR, Methodist Health System

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-02
Study Completion Date2024-08-02

Study Record Updates

Study Start Date2023-08-02
Study Completion Date2024-08-02

Terms related to this study

Additional Relevant MeSH Terms

  • Prostate Cancer