RECRUITING

Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators aim to conduct a randomized controlled trial to compare two symptom-management programs for Black older adults with early cognitive decline (self-reported confirmed by testing) and chronic pain. The programs are Mindfulness-Based Cognitive Therapy with Walking (MBCT+w) and Active Living Every Day (ALED). The investigators will assess how each program may help in improving physical, cognitive, and emotional function. The investigators will also assess whether improvements in outcomes from the two programs are maintained through a 6-month follow-up.

Official Title

Comorbidity of Chronic Pain and Early Cognitive Decline Among Older, Community-Based Black Adults: Comparative Effectiveness of Mindfulness-Based Cognitive Therapy With Walking (MBCT+w) vs Active Living Every Day (ALED)

Quick Facts

Study Start:2025-01-10
Study Completion:2028-11-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06246929

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Black adults, male and females, age 50 or older
  2. * Have nonmalignant musculoskeletal chronic pain for more than three months
  3. * Reports early cognitive decline (subjective and objective)
  4. * Telephone Interview for Cognitive Status-41 score greater than or equal to 31
  5. * Functional Activities Questionnaire score less than 9
  6. * English fluency/literacy
  7. * Free of concurrent psychotropic or pain medication for at least 2 weeks prior to initiation of treatment, OR stable on current psychotropic or pain medication for a minimum of 6 weeks and willing to maintain stable dose
  8. * Cleared by medical doctor for study participation and no self-reported concerns about physical functioning on the revised Physical Activity Readiness Questionnaire (PAR-Q; score 0)
  1. * Diagnosed with dementia or neurodegenerative disease
  2. * Regular use of nonpharmacological pain management
  3. * Diagnosed with serious mental illness or substance abuse
  4. * Current suicidal ideation on self-report
  5. * Engagement of regular exercise for more than 30 minutes daily
  6. * Unable to walk

Contacts and Locations

Study Contact

Mallory Morehead, MPH
CONTACT
(978) 580-3153
mmorehead@mgb.org
Adjoa Acquaah, BA
CONTACT
(617) 726-8103
aacquaah@mgh.hardvard.edu

Principal Investigator

Olivia Okereke, MD, MS
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital

Study Locations (Sites)

Massachusetts General Hospital
Boston, Massachusetts, 02114
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Olivia Okereke, MD, MS, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-10
Study Completion Date2028-11-01

Study Record Updates

Study Start Date2025-01-10
Study Completion Date2028-11-01

Terms related to this study

Keywords Provided by Researchers

  • Black Older Adults
  • African Americans
  • Subjective Cognitive Decline
  • Memory Related Problems
  • Pain
  • Cognition Disorders

Additional Relevant MeSH Terms

  • Chronic Pain
  • Physical Activity
  • Older Adults
  • Mild Cognitive Impairment