Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Description

People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert. In this project, the investigators seek to further translate knowledge about interpreting brain signals related to movement, and to further develop an intracortical brain-computer interface (iBCI) that could restore rapid and intuitive use of communication apps on tablet computers by people with paralysis.

Conditions

Brainstem Stroke, ALS, Tetraplegia, Spinal Cord Injuries, Cervical Spinal Cord Injury

Study Overview

Study Details

Study overview

People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert. In this project, the investigators seek to further translate knowledge about interpreting brain signals related to movement, and to further develop an intracortical brain-computer interface (iBCI) that could restore rapid and intuitive use of communication apps on tablet computers by people with paralysis.

Intuitive, Complete Neural Control of Tablet Computers for Communication

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Condition
Brainstem Stroke
Intervention / Treatment

-

Contacts and Locations

Boston

Masssachusetts General Hospital, Boston, Massachusetts, United States, 02114

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy, amyotrophic lateral sclerosis or other motor neuron disorders
  • * Complete or incomplete tetraplegia (quadriplegia)
  • * Must live within a three-hour drive of the Study site
  • * Prior enrollment in BrainGate2 clinical trial (NCT00912041)
  • * Visual impairment such that extended viewing of a computer monitor would be difficult even with ordinary corrective lenses
  • * Chronic oral or intravenous steroids or immunosuppressive therapy
  • * Other serious disease or disorder that could seriously affect ability to participate in the study

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Leigh R. Hochberg, MD, PhD.,

Leigh R Hochberg, MD, Ph.D., PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

2027-07-30