ACTIVE_NOT_RECRUITING

Trial of Pistachio Consumption in Older Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to evaluate whether a pistachio-enriched diet leads to changes in cognitive function, cardiometabolic risk factors, and life satisfaction in older adults over a 6-month period.

Official Title

Trial of Pistachio Consumption on Cognition, Cardiometabolic Risk Factors, and Life Satisfaction in Older Adults

Quick Facts

Study Start:2025-05-28
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT06992544

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:65 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Active participant in COSMOS
  2. 2. Current age 65 to 80 years
  1. 1. Tree nut allergy
  2. 2. Current intake of peanuts, walnuts, or other nuts \>1 serving/week
  3. 3. Diagnosis of Alzheimer's disease or any other type of dementia
  4. 4. Diagnosis of cancer or CVD (MI, stroke, CABG, PTCA, or stent) within last 12 months
  5. 5. Changes in the dose or number of anti-hypertensive, lipid-lowering, or diabetic medications over the past 3 months prior to randomization
  6. 6. Does not own a smartphone or tablet
  7. 7. Unable or unwilling to abstain from pistachio intake for 6 months
  8. 8. Unable or unwilling to limit nut consumption to ≤1 serving/week for 6 months
  9. 9. Unable or unwilling to complete online questionnaires and cognitive assessments
  10. 10. Unable or unwilling to travel to a local Quest site for biospecimen collection
  11. 11. Unable or unwilling to provide consent to participate in the trial
  12. 12. Failure to complete the baseline Life Satisfaction Questionnaire
  13. 13. Failure to complete the baseline cognitive assessments
  14. 14. Failure to complete the baseline biospecimen collection

Contacts and Locations

Study Locations (Sites)

Brigham and Women's Hospital
Boston, Massachusetts, 02215
United States

Collaborators and Investigators

Sponsor: Brigham and Women's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-05-28
Study Completion Date2026-06

Study Record Updates

Study Start Date2025-05-28
Study Completion Date2026-06

Terms related to this study

Keywords Provided by Researchers

  • Pistachio
  • Cognition
  • Life satisfaction
  • Older adults
  • Cardiometabolic risk factors
  • Blood pressure
  • Biomarkers
  • Memory
  • Diet
  • Nut intake

Additional Relevant MeSH Terms

  • Cognition
  • Cardiometabolic Risk Factors
  • Life Satisfaction