Trial of Pistachio Consumption in Older Adults

Description

The goal of this study is to evaluate whether a pistachio-enriched diet leads to changes in cognitive function, cardiometabolic risk factors, and life satisfaction in older adults over a 6-month period.

Conditions

Cognition, Cardiometabolic Risk Factors, Life Satisfaction

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Study Overview

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Study Details

Study overview

The goal of this study is to evaluate whether a pistachio-enriched diet leads to changes in cognitive function, cardiometabolic risk factors, and life satisfaction in older adults over a 6-month period.

Trial of Pistachio Consumption on Cognition, Cardiometabolic Risk Factors, and Life Satisfaction in Older Adults

Trial of Pistachio Consumption in Older Adults

Condition
Cognition
Intervention / Treatment

-

Contacts and Locations

Boston

Brigham and Women's Hospital, Boston, Massachusetts, United States, 02215

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Active participant in COSMOS
  • 2. Current age 65 to 80 years
  • 1. Tree nut allergy
  • 2. Current intake of peanuts, walnuts, or other nuts \>1 serving/week
  • 3. Diagnosis of Alzheimer's disease or any other type of dementia
  • 4. Diagnosis of cancer or CVD (MI, stroke, CABG, PTCA, or stent) within last 12 months
  • 5. Changes in the dose or number of anti-hypertensive, lipid-lowering, or diabetic medications over the past 3 months prior to randomization
  • 6. Does not own a smartphone or tablet
  • 7. Unable or unwilling to abstain from pistachio intake for 6 months
  • 8. Unable or unwilling to limit nut consumption to ≤1 serving/week for 6 months
  • 9. Unable or unwilling to complete online questionnaires and cognitive assessments
  • 10. Unable or unwilling to travel to a local Quest site for biospecimen collection
  • 11. Unable or unwilling to provide consent to participate in the trial
  • 12. Failure to complete the baseline Life Satisfaction Questionnaire
  • 13. Failure to complete the baseline cognitive assessments
  • 14. Failure to complete the baseline biospecimen collection

Ages Eligible for Study

65 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Brigham and Women's Hospital,

Study Record Dates

2026-06