RECRUITING

Steroid Treatment for Elimination of Rebound Obstruction From Intranasal Decongestants

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This prospective, virtually administered trial conducted throughout the United States aims to evaluate a standardized protocol including the serial dilution of topical decongestants with concurrent topical steroids (triamcinolone), for elimination of dependence on topical decongestants.

Official Title

Steroid Treatment for Elimination of Rebound Obstruction From Intranasal Decongestants

Quick Facts

Study Start:2025-09-09
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT07168148

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. 1. Any history of sinonasal mass/tumor
  2. 2. Any history of nasal polyps
  3. 3. Septal perforation
  4. 4. A diagnosis of one of the following conditions:
  5. 1. eosinophilic granulomatosis with polyangiitis
  6. 2. granulomatosis with polyangiitis
  7. 5. Any current intranasal drug use such as cocaine.
  8. 6. If they are currently using or have used intranasal steroid medications (oral or nasal) besides oxymetazoline for the past month.

Contacts and Locations

Study Contact

Nyssa Farrell, MD
CONTACT
314-362-7509
nyssa.farrell@wustl.edu
Sara Kukuljan
CONTACT
314-362-7563
kukuljas@wustl.edu

Principal Investigator

Nyssa Farrell, MD
PRINCIPAL_INVESTIGATOR
Washington University School of Medicine

Study Locations (Sites)

Washington University
St Louis, Missouri, 63110
United States

Collaborators and Investigators

Sponsor: Washington University School of Medicine

  • Nyssa Farrell, MD, PRINCIPAL_INVESTIGATOR, Washington University School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-09-09
Study Completion Date2026-12

Study Record Updates

Study Start Date2025-09-09
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • topical intranasal corticosteroid management
  • nasal airway evaluation
  • triamcinolone
  • oxymetazoline

Additional Relevant MeSH Terms

  • Nasal Obstruction
  • Chronic Rhinitis